HEREDITARY TENDENCY

Bleeding tendency in uremia.

LTHOIJGH the association of bleeding teuideuicy with uremia has beeui recognized fon’ at least a century,n the exact (‘ause has miever 1)een clearly defined. Vascular damage has been suggested.2 This study includes assays of many hemostatic factors in twelve patients showing varying degrees of azotelllia with and without hemorrhagic manifestations. An abnormality in platelet function (thrombocy...

[Evaluation of suicidal tendency].

The Streptococcal Tendency

Decreased coagulability has no clinically relevant effect on atherogenesis: observations in individuals with a hereditary bleeding tendency.

BACKGROUND Hemostasis affects ischemic cardiovascular disease through its role in formation of occluding arterial thrombi. Several studies suggest that hemostasis also might play a role in atherogenesis. We investigated whether individuals with an inherited bleeding tendency are protected against development of atherosclerosis. METHODS AND RESULTS A total of 76 individuals with an inherited b...

Genetic tendency in Crohn's disease.

A fifth instance of Crohn's disease in identical twins is reported. The evidence for genetic expression of the disease is considered and the possible mechanisms involved are reviewed.